Although Zegerid powder for oral suspension is currently indicated for adults, it can be used in children when mixed according to these instructions. Omeprazole, the active ingredient in Zegerid, is approved for use in children. The only other PPI approved for use in children (under 12 years old) is lansoprazole.

If your child is 2 years of age or younger, it is generally best to use the 40mg packet of Zegerid with Mylanta Cherry Supreme. The higher ratio of bicarb of the 20mg packets of Zegerid may cause trouble with some infants (vomiting, gas, taste aversion or refusal to take). This can be counteracted by switching to the 40 mg packets and adding one equal part Mylanta Cherry Supreme. For example, let’s say your child’s dose is 8mg, three times daily. You will give 2mL of the suspension (because the concentration of the suspension is 4mg/mL, and 4mg/1mL = 8mg/2mL), along with one equal part (2mL) Mylanta Cherry Supreme, three times a day.

Resultant volume: 10 mL
Concentration: 4 mg per 1 mL of suspension
Stability: 28 days when refrigerated, 7 days at room temperature*

Prior to use, shake well.
Between each use, keep refrigerated.

Click for more information on the 20 mL oral dosing syringe used in preparing the suspension.

1. Open Zegerid packet and carefully set aside.

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2. Prepare a 20 mL oral dosing syringe by removing the stopper

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3. Cap the opening with a tip cap.

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4. Pour 6.5 mL of water into the syringe.

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5. Pour the contents of the Zegerid packet into the syringe, and reinsert the stopper.

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6. Invert the syringe and carefully remove the cap. Gently push the stopper to remove the air from the syringe. Replace the cap.

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7. Shake vigorously until the powder is completely dissolved.

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*Burnett J, Balkin E.  Stability and viscosity of a flavored omeprazole oral suspension for peditric use. Am J Health-Syst Pharm Vol 63; Nov 15, 2006